Is sessions) [17]. Evenepoel et al. performed a monocenter, prospective, randomized trial including 33 hemodialysis patients at high risk of bleeding, in whom regional anticoagulation was
achieved by means of either AN69 ST (Nephral ST; 11 patients, 31 sessions), RCA-Ca0 (11 patients,
4-Diacetyl-2 32 sessions) or RCA-Ca3.0 (11 patients, 30 sessions).
Clotting phenomena necessitating premature termination of the dialysis session were encountered in 39 , 13 and 0 using AN69 ST, RCA-Ca3.0 and RCA-Ca0, respectively (P <0.005). The authors concluded to the superiority of citrate regional anticoagulation [19]. In a bicentric, Austrian, randomized, crossover trial, Kodras et al. treated 10 patients receiving oral anticoagulants with AN69 ST and FX 100 (a polysulfone membrane) for 1 week (total 30 sessions of heparin-free dialysis, with only priming of the dialyzer and no systemic heparinization).
